Well, there is an analytical or deconstructive approach which derives from scientific methods of inquiry and perhaps from Western culture.
But there's also the record of science's having advanced as a result of its hyperskepticism which has undermined all kinds of myths and intuitions. So maybe the commonsense conception of the self as a mind is the next bubble to burst. That's what motivates the eliminativist.
Then there's the question of whether the folk conception of the self is in fact consistent with the neuroscientific conception. Are consciousness, rationality, freewill, meanings, values, and beliefs and desires real as they're commonly conceived or are they illusory?