That's a good, existential answer, which takes life to be absurd or pointless.
But by "mystic" I had in mind naturalistic monists such as pantheists, Daoists, and Buddhists (who speak of everything as being dependently originated, and thus as causally related). It's that naturalism that entails a scientific, empirical perspective on understanding how everything comes to be, and evolutionary causality implies a natural purpose or role.
The question for such monists who disavow the humanistic dichotomy between personhood and wilderness is where we fit into nature's larger patterns or causal relations.
Sure, a token flower in a field wouldn't have much of a cosmic role, but I'm talking about life in general.