Personally I go back and forth between the sweeping, naturalistic (Daoist) and humanistic perspectives, between cosmicism and existentialism.

I agree with your last point, which is why I think humanism entails transhumanism.

https://medium.com/illumination-curated/the-stakes-of-transhuman-godhood-7a5b39bf0433?sk=37652a96a645529b50ee3059237a5d11

https://medium.com/gods-funeral/is-technology-turning-our-species-into-a-new-force-of-nature-6d9e00ff34e1?sk=35eaa0604dfac30c350400817c4ce33a

https://medium.com/illumination-curated/should-transhumanists-be-pessimistic-about-human-nature-2c2f46122fb7?sk=ab2fdb107eea4a099fe22c9a7a9d74c0