I wouldn't call it "fate," since some nice guys succeed. Talent can speak for itself, which propels some artists into the spotlight, for instance, even as most starve.

I've written a lot on the distinction between the natural and the artificial, and I'd maintain that human society is natural only in a vacuous sense of "natural," the kind that would include black holes as natural even as black holes literally gobble up the natural order. We can always eliminate dichotomies by weakening the meaning of our words, which leads to mystical monism, including Taoism.

I prefer a more pragmatic, naturalistic philosophy, one that sees the utility of the distinction between the natural and the artificial. According to that distinction, human progress represents an anomaly like black holes, an anti-natural backlash via consciousness and intelligence. Granted, that backlash is likely doomed to be tragically incomplete, as I think you say, even given transhumanist prophecies. But I suspect that will be the thrust of the human narrative: a tragic revolt against nature's inhumanity (where "nature" includes everything we haven't yet humanized or technologically transformed/pacified).