I agree that the simplification is immensely useful. Indeed, we could hardly think at all without simplifying the subject matter since our brainpower is limited. But the temptation is to mistake the map for the territory. This is what Buddhists emphasize, the danger of becoming too attached to our brainchildren, to the proliferation of concepts.

Our conceptions might be so abstract that they're effectively stereotypes like stick-man figures. There's an immense difference between a real person and a stick-man figure, or between a real tree and a stereotypical conception of trees. So the conceptions are useful, but they're useful precisely because they simplify, which means they're only partially accurate or realistic. They leave out some information, which means they might lie by omission. That's the kind of falsification I have in mind.

Think also of Plato's idea of noble lies (religious myths). Some falsifications can be quite useful.